The circular dated October 29, 2021 is regarding list of alternate activities for Science Practical work for classes 9-10 curated by CBSE using simple, readily available household materials that learners can use to do these activities at their homes. The hands-on activities have been designed to have similar learning outcomes for all the lab experiments required to be done in 21-22 for class 9 and 10. Besides this, a list of additional activities from the NCERT lab manual for 9 (20 activities) and 10 (22 activities) are provided. These hands-on activities are accompanied by step-by-step guides, videos and worksheets for students to record observations. A list of material needed for each experiment, together with alternatives have also been included in the content package to facilitate the learners. The list of the class 9 and 10 lab experiments and the links to access hands-on activities that can be used as an alternative is detailed as Annexures in the document.